Articles
ANTIOXIDATIVE ACTIVITY OF KHAT (CATHA EDULIS FORSK.)
Article number
778_8
Pages
85 – 92
Language
English
Abstract
Catha edulis Forsk. (khat) is an evergreen tree growing wild in high altitudes in East Africa and the Arabian Peninsula.
Due to its stimulating effect, chewing fresh young leaves of khat has become a common habit in several countries in those regions, which later spread to the Western world.
The stimulating activity of khat is attributed to its alkaloid fraction, comprising mainly of cathine and cathinone.
In addition to its everyday use, khat has been known as a traditional medicinal plant for centuries.
Therefore, additional aspects concerning this species secondary metabolism and its related biological activity are currently examined.
In an attempt to identify new potential plant sources for antioxidants, khat varieties were found to posses a substantial antioxidative activity, ranging 175–204 mg/g DW chlorogenic acid equivalent.
Cathine and cathinone were found to have a negligible contribution to the antioxidative activity.
In order to estimate the potential use of Catha edulis as a natural antioxidant source, further aspects such as plant material availability, extraction efficiency and safety issues are yet to be evaluated.
Due to its stimulating effect, chewing fresh young leaves of khat has become a common habit in several countries in those regions, which later spread to the Western world.
The stimulating activity of khat is attributed to its alkaloid fraction, comprising mainly of cathine and cathinone.
In addition to its everyday use, khat has been known as a traditional medicinal plant for centuries.
Therefore, additional aspects concerning this species secondary metabolism and its related biological activity are currently examined.
In an attempt to identify new potential plant sources for antioxidants, khat varieties were found to posses a substantial antioxidative activity, ranging 175–204 mg/g DW chlorogenic acid equivalent.
Cathine and cathinone were found to have a negligible contribution to the antioxidative activity.
In order to estimate the potential use of Catha edulis as a natural antioxidant source, further aspects such as plant material availability, extraction efficiency and safety issues are yet to be evaluated.
Authors
N. Dudai, R. Fischer, D. Segev, D. Chaimovitsh, N. Rosenzweig, M. Shimoni
Keywords
antioxidants, cathine, cathinone, Catha edulis, total phenol content, DPPH
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