Articles
CHEMICAL ANALYSIS AND ANTITUMOR ACTIVITY OF NATURAL AND SEMI-NATURAL CAROTENOIDS OF SAFFRON
Article number
650_55
Pages
447 – 461
Language
English
Abstract
The qualitative analysis and determination of saffron components using chromatographic and spectroscopic methods is described.
Combination of LC-MS data with UV-Vis, FT-IR, FT-Raman and 1H NMR and crystal structure analysis data prove useful information in identifying of saffron compounds.
In addition, the effects of saffron carotenoids on cell proliferation and differentiation of K562 and HL-60 cells cancer human cell lines in vitro are demonstrated.
Combination of LC-MS data with UV-Vis, FT-IR, FT-Raman and 1H NMR and crystal structure analysis data prove useful information in identifying of saffron compounds.
In addition, the effects of saffron carotenoids on cell proliferation and differentiation of K562 and HL-60 cells cancer human cell lines in vitro are demonstrated.
Authors
P.A. Tarantilis, M.G. Polissiou
Keywords
Crocus sativus L., FT-IR, FT-Raman and 1H NMR, human leukemic cells, LC-MS, UV-Vis, X-ray
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