Articles
PREVENTION OF COLD STRESS INDUCED ADRENAL HYPERTROPHY BY SPIRULINA PLATENSIS
Article number
680_14
Pages
101 – 107
Language
English
Abstract
Spirulina platensis (Spirulina) was investigated on an acute stress (4h cold stress, 4±1°C) induced biochemical alteration in albino rats.
Gastric ulcerations, adrenal gland weight, adrenal gland ascorbic acid content, and histopathology were also used as stress indices. Panax ginseng (ginseng) was used as standard adaptogenic agent for comparison.
Acute cold stress resulted in elevation of blood glucose levels, increase in adrenal gland weight, and reduction in adrenal gland ascorbic acid content and histological changes.
Spirulina (100 mg/kg, 200 mg/kg and 500 mg/kg p.o.) and ginseng (100 mg/kg p.o.) attenuated all these cold stress induced perturbations.
Results demonstrated the anti-stress activity of Spirulina, qualitatively comparable to ginseng, against a variety of biochemical and histological perturbations induced by acute cold stress.
Gastric ulcerations, adrenal gland weight, adrenal gland ascorbic acid content, and histopathology were also used as stress indices. Panax ginseng (ginseng) was used as standard adaptogenic agent for comparison.
Acute cold stress resulted in elevation of blood glucose levels, increase in adrenal gland weight, and reduction in adrenal gland ascorbic acid content and histological changes.
Spirulina (100 mg/kg, 200 mg/kg and 500 mg/kg p.o.) and ginseng (100 mg/kg p.o.) attenuated all these cold stress induced perturbations.
Results demonstrated the anti-stress activity of Spirulina, qualitatively comparable to ginseng, against a variety of biochemical and histological perturbations induced by acute cold stress.
Publication
Authors
R.S. Nachankar, A.R. Juvekar, A. Sonawane
Keywords
adaptogenic, ascorbic acid content, plasma glucose levels, ulcer
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