Articles
IMMUNOMODULATORY EFFECTS OF GYNOSTEMMA PENTAPHYLLUM MAKINO ON HUMAN IMMUNE CELLS
Article number
680_25
Pages
165 – 169
Language
English
Abstract
Use of herbs as health and/or dietary supplements has increased worldwide.
The most common usage of botanicals is to improve the immune system.
Water extract of Gynostemma pentaphyllum Makino was studied for its effects on lymphocyte proliferation and natural killer (NK) cell activity.
Lymphocyte proliferation of normal peripheral blood mononuclear cells (PBMC) in response to G. pentaphyllum extract was increased at concentrations of (in ng/mL) 1, 10, 100, and (in µg/mL) 1, 5, 10 and 100. Aqueous extract of G. pentaphyllum reduced lymphocyte proliferation at 1 µg/mL, suggesting immunomodulating activities on human immunocompetent PBMC.
The most common usage of botanicals is to improve the immune system.
Water extract of Gynostemma pentaphyllum Makino was studied for its effects on lymphocyte proliferation and natural killer (NK) cell activity.
Lymphocyte proliferation of normal peripheral blood mononuclear cells (PBMC) in response to G. pentaphyllum extract was increased at concentrations of (in ng/mL) 1, 10, 100, and (in µg/mL) 1, 5, 10 and 100. Aqueous extract of G. pentaphyllum reduced lymphocyte proliferation at 1 µg/mL, suggesting immunomodulating activities on human immunocompetent PBMC.
Publication
Authors
B. Sriwanthana, W. Threesangsri, W. Wanavichet, P. Chavalittumrong, J. Bansiddhi, Y. Techadamrongsin
Keywords
immunomodulator, jiaogulan, lymphocyte proliferation, NK cell activity
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