Articles
CO2-EXTRACT FROM GERMAN CHAMOMILE-PROPOSED MEDICINAL USE
Article number
503_1
Pages
15 – 20
Language
Abstract
The CO2-extract from German chamomile contains the lipophilic components of the flowerheads.
Compared with the essential oil, its drug-product ratio is lower and its composition is slightly different.
In the pharmacological model of the arachidonic acid cascade, it shows anti-inflammatory properties according to the higher drug-product ratio compared with a “normal” alcoholic extract.
Its wound-healing properties should be further evaluated.
In the mouse ear edema, it shows a significant, but weaker activity than hydrocortisone.
Its use in a treatment scheme of the atopic eczema is promising.
However, further clinical evidence is needed.
Compared with the essential oil, its drug-product ratio is lower and its composition is slightly different.
In the pharmacological model of the arachidonic acid cascade, it shows anti-inflammatory properties according to the higher drug-product ratio compared with a “normal” alcoholic extract.
Its wound-healing properties should be further evaluated.
In the mouse ear edema, it shows a significant, but weaker activity than hydrocortisone.
Its use in a treatment scheme of the atopic eczema is promising.
However, further clinical evidence is needed.
Authors
B. Hempel
Keywords
Matricaria, anti-inflammatory properties, atopic eczema, clinical study
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