Articles
Development of antioxidant gelatin films using corn and nopal-derived biopolymers for potential topical treatments
Article number
1452_48
Pages
367 – 376
Language
English
Abstract
This study explores the enhancement of gelatin-based films by incorporating cellulose from corn cob and polysaccharides from nopal pads to improve their effectiveness for topical applications.
Three types of films were developed: a gelatin-only film, a film reinforced with cellulose and polysaccharides extracted from corn cob and nopal, and a third film incorporating a phenolic-rich extract obtained from the hydrolysis of both agro-industrial residues.
The films were evaluated for their antioxidant activity using Folin-Ciocalteu, DPPH, and ABTS assays.
The addition of the phenolic-rich extract significantly enhanced the films’ antioxidant properties.
While all films demonstrated moisture retention capabilities, the gelatin-only film exhibited the highest water absorption.
However, the incorporation of cellulose and polysaccharides improved the films’ mechanical stability and facilitated the controlled release of bioactive compounds, making them promising candidates for wound healing, anti-inflammatory treatments, and prolonged therapeutic delivery.
By revalorizing agricultural by-products, this study provides an eco-friendly and cost-effective alternative to conventional hydrocolloids used in biomedical and skincare industries.
Three types of films were developed: a gelatin-only film, a film reinforced with cellulose and polysaccharides extracted from corn cob and nopal, and a third film incorporating a phenolic-rich extract obtained from the hydrolysis of both agro-industrial residues.
The films were evaluated for their antioxidant activity using Folin-Ciocalteu, DPPH, and ABTS assays.
The addition of the phenolic-rich extract significantly enhanced the films’ antioxidant properties.
While all films demonstrated moisture retention capabilities, the gelatin-only film exhibited the highest water absorption.
However, the incorporation of cellulose and polysaccharides improved the films’ mechanical stability and facilitated the controlled release of bioactive compounds, making them promising candidates for wound healing, anti-inflammatory treatments, and prolonged therapeutic delivery.
By revalorizing agricultural by-products, this study provides an eco-friendly and cost-effective alternative to conventional hydrocolloids used in biomedical and skincare industries.
Authors
L.V. Bonifaz Delgado, D.E. Mejía Valdez, D. Guajardo Flores
Keywords
gelatin hydrocolloids, corn cob cellulose, nopal polysaccharides, antioxidant activity, drug delivery
Groups involved
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