Articles
EVALUATION STUDIES ON KALMEGH (ANDROGRAPHIS PANICULATA NEES)
Article number
972_15
Pages
117 – 120
Language
English
Abstract
Andrographis paniculata nees (Acanthaceae), the kalmegh of Ayurveda in India is an annual herb, widely used in the Indian system of medicine as a stomachic, tonic, antipyretic, anti-fertility, anti-inflammatory, antibacterial, antiviral, immuno-stimulatory and anti-oxidant agent.
Androgropholide is the major active principle present in the plant attributing therapeutic activity.
Kalmegh is a component of over 50% of the multi-ingredient herbal formulations available in India for the treatment of liver ailments.
The herb is widely distributed in plains and forests throughout India.
A study on evaluation of wild growing populations collected from diverse locations was initiated to identify a suitable genotype with high andrographolide content.
Andrographolide content ranged from 1.30 to 2.51% among 22 collections with mean andrographolide of 1.82%. Promising collections identified were IC342139 (2.51%), IC471916 (2.16%), IC111291 (2.20%) and IC210635 (2.13%). Considering its value as a drug raw material, emphasis should be given for its commercial cultivation to get authentic raw material of known quality.
Androgropholide is the major active principle present in the plant attributing therapeutic activity.
Kalmegh is a component of over 50% of the multi-ingredient herbal formulations available in India for the treatment of liver ailments.
The herb is widely distributed in plains and forests throughout India.
A study on evaluation of wild growing populations collected from diverse locations was initiated to identify a suitable genotype with high andrographolide content.
Andrographolide content ranged from 1.30 to 2.51% among 22 collections with mean andrographolide of 1.82%. Promising collections identified were IC342139 (2.51%), IC471916 (2.16%), IC111291 (2.20%) and IC210635 (2.13%). Considering its value as a drug raw material, emphasis should be given for its commercial cultivation to get authentic raw material of known quality.
Authors
A.P. Raina, A. Kumar, S.K. Pareek, S.K. Sharma
Keywords
Andrographis paniculata, andrographolide, germplasm, HPTLC
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