Articles
ANTICANCER AGENT FROM ALBIZZIA LEBBEK
Article number
188_7
Pages
69 – 82
Language
Abstract
Alkaloids of different chemical nature were isolated from an indigenous plant Albizzia lebbek Benth family leguminocae, subfamily mimosae.
These alkaloids were fractionated and isolated by thin layer and column chromatography.
The alkaloid content of the seeds of this plant was found to be the highest in amount.
Three alkaloids were isolated from the seeds and one of them which showed maximum cytotoxic activity against Neurospora crassa had been isolated in pure form and attempts were made to characterise it by various physico-chemical methods such as elemental analysis, chemical tests, UV, IR, Mass and H-NMR spectroscopy.
The compound was also found to be active against P-388 cell line.
These alkaloids were fractionated and isolated by thin layer and column chromatography.
The alkaloid content of the seeds of this plant was found to be the highest in amount.
Three alkaloids were isolated from the seeds and one of them which showed maximum cytotoxic activity against Neurospora crassa had been isolated in pure form and attempts were made to characterise it by various physico-chemical methods such as elemental analysis, chemical tests, UV, IR, Mass and H-NMR spectroscopy.
The compound was also found to be active against P-388 cell line.
Authors
N. Rahman, S. Aktar, C. M. Hasan, A. Jabbar
Keywords
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