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Articles

BIOTECHNOLOGICAL STRATEGIES FOR PRODUCTION OF PLANTS AND SECONDARY METABOLITES OF PHARMACEUTICAL INTEREST

Article number
502_44
Pages
269 – 280
Language
Abstract
Biotechnological approaches are of increasing application and use for medicinal plants and secondary metabolite production.
Micropropagation allows the production of pathogen-free plants with uniform quality for agronomic cultures and also for germplasm conservation.
Plant in vitro culture allows the production of secondary metabolites under controlled culture conditions.
Two types of in vitro cultures are currently used for secondary metabolite production: dedifferentiated cultures (callus and suspension cultures) and differentiated cultures (transformed roots and shoots). The former tends to accumulate secondary metabolites only in small amount compared to the whole plant.
The approaches used for increasing the production of secondary metabolites include optimization of growth and production culture media, as well as elicitation and metabolic engineering.

Publication
Authors
A.M. Giulietti, R.J. Ertola
Keywords
Secondary metabolites, biotechnological strategies, in vitro cultures, transgenic plants
Full text
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