Articles
STRUCTURE AND IMMUNOLOGICAL ACTIVITY OF A POLYSACCHARIDE (JUBP-1) FROM THE FRUIT OF CHINESE JUJUBE
Article number
853_41
Pages
345 – 350
Language
English
Abstract
Chinese jujube (Ziziphus jujuba Mill.) is a perennial woody plant famous for its nutritious fruit, a traditional invigorant in the East and Southeast Asia.
A polysaccharide (JuBP-1) was isolated from the fruit of Ziziphus jujuba Jinsixiaozao and its structure was characterized by acid hydrolysis, methylation and NMR spectroscopies.
JuBP-1 has a molecular mass of over 2000 KDa with [
]20D+101(c=1.05, H2O). It is composed of rhamnose, arabinose, galactose and galacturonic acid in a molar ratio of 1:4.3:3.2:21.4. The main backbone chain in JuBP-1 is mostly composed with (1→4)-linked α-D-GalA interspersed with 1,2-linked -L-Rha and the side chains was mainly 1,5 linked –Araf residues attached to O-4 of rhamnose residues.
In vitro test revealed that JuBP-1 (10–100 μg/ml) had significant (P<0.01) immunoenhancing effect on spleen cells proliferation in a dose-dependent manner.
A polysaccharide (JuBP-1) was isolated from the fruit of Ziziphus jujuba Jinsixiaozao and its structure was characterized by acid hydrolysis, methylation and NMR spectroscopies.
JuBP-1 has a molecular mass of over 2000 KDa with [
]20D+101(c=1.05, H2O). It is composed of rhamnose, arabinose, galactose and galacturonic acid in a molar ratio of 1:4.3:3.2:21.4. The main backbone chain in JuBP-1 is mostly composed with (1→4)-linked α-D-GalA interspersed with 1,2-linked -L-Rha and the side chains was mainly 1,5 linked –Araf residues attached to O-4 of rhamnose residues.In vitro test revealed that JuBP-1 (10–100 μg/ml) had significant (P<0.01) immunoenhancing effect on spleen cells proliferation in a dose-dependent manner.
Authors
Z.H. Zhao, M.J. Liu
Keywords
Ziziphus jujube, ¿Jinsixiaozao¿, fruit, polysaccharide, immunological activity
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