Articles
MAPPING DISEASE RESISTANCE GENES IN TOMATO: A TOY FOR THE GENETICIST OR A JOY FOR THE BREEDER?
Article number
412_2
Pages
39 – 48
Language
Abstract
For tomato, basically three different strategies have been used for disease resistance gene mapping: 1) considering cultivars as nearly isogenic lines 2) cosegregation of markers with disease resistance genes in interspecific populations and 3) QTL mapping.
These three approaches have proven to be highly successful and today, at least 25 disease resistance genes have already been mapped.
This number will surely increase in the near future.
Molecular geneticists may take advantage of molecular markers by studying gene effects separately in greater detail.
One of the most promising potentials is in the field of gene isolation by map based cloning.
This will enable the most detailed study of disease resistance gene function.
Also, the advantages for breeding programmes are numerous.
It is expected that the most important application will be the selection for quantitative traits.
The finding of molecular markers linked to QTLs for these traits is laborious and tedious.
However, once a QTL for a quantitative trait has been clarified, the breeding perspectives are higher.
These three approaches have proven to be highly successful and today, at least 25 disease resistance genes have already been mapped.
This number will surely increase in the near future.
Molecular geneticists may take advantage of molecular markers by studying gene effects separately in greater detail.
One of the most promising potentials is in the field of gene isolation by map based cloning.
This will enable the most detailed study of disease resistance gene function.
Also, the advantages for breeding programmes are numerous.
It is expected that the most important application will be the selection for quantitative traits.
The finding of molecular markers linked to QTLs for these traits is laborious and tedious.
However, once a QTL for a quantitative trait has been clarified, the breeding perspectives are higher.
Authors
P. Lindhout
Keywords
Lycopersicon esculentum, NILs, QTL mapping, molecular markers
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