Articles
FvMAPK6 acts as a central phosphorylation hub governing sucrose signaling and sugar accumulation in strawberry fruit
Article number
1465_26
Pages
155 – 166
Language
English
Abstract
The mechanisms underlying sugar accumulation and signaling in fruits remain largely unexplored.
Here, we report that FvMAPK6 is a phosphorylation hub controlling anthocyanin and sugar accumulation and sucrose signaling in strawberry (Fragaria spp.) fruits.
The phosphorylation of components involved in sugar signaling and accumulation, including key regulators such as FvSnRK1α and FvMYB44.2, was altered in FvMAPK6-overexpressing (FvMAPK6-OE) or gene-edited mutant (Fvmapk6-cr) fruits.
Our results indicate that sucrose signaling activates FvMAPK6, initiating a phosphorylation cascade with FvMAPKK4 to directly phosphorylate the transcription factors FvMYB44.1 and FvMYB44.2, thereby regulating their stability and transcriptional activity and modulating the expression of genes involved in anthocyanin biosynthesis, sugar metabolism, and transport.
FvMAPK6 also increased the phosphorylation and abundance of hexose transporter FvSWEET1 to facilitate sugar accumulation during sucrose signaling.
Here, we report that FvMAPK6 is a phosphorylation hub controlling anthocyanin and sugar accumulation and sucrose signaling in strawberry (Fragaria spp.) fruits.
The phosphorylation of components involved in sugar signaling and accumulation, including key regulators such as FvSnRK1α and FvMYB44.2, was altered in FvMAPK6-overexpressing (FvMAPK6-OE) or gene-edited mutant (Fvmapk6-cr) fruits.
Our results indicate that sucrose signaling activates FvMAPK6, initiating a phosphorylation cascade with FvMAPKK4 to directly phosphorylate the transcription factors FvMYB44.1 and FvMYB44.2, thereby regulating their stability and transcriptional activity and modulating the expression of genes involved in anthocyanin biosynthesis, sugar metabolism, and transport.
FvMAPK6 also increased the phosphorylation and abundance of hexose transporter FvSWEET1 to facilitate sugar accumulation during sucrose signaling.
Publication
Authors
Q.Q. Feng, L.Z. Wei, T. Liu, K.X. Wang, X.J. Li, C. Liu, R.H. Sun, X. Li, Z.N. Yin, Y.Q. Wei, H.Z. Yuan, Q. Li, B.B. Li
Keywords
Fragaria, FvMAPK6, sucrose signaling, sugar accumulation, anthocyanin biosynthesis
Groups involved
- Division Vine and Berry Fruits
- Working Group Strawberry Culture and Management
- Division Sustaining Horticulture in a Changing World
- Division Horticulture for Human Health
- Division Plant Genetic Resources, Breeding and Biotechnology
- Division Greenhouse and Indoor Production Horticulture
- Division Precision Horticulture and Engineering
Online Articles (64)